OUR LABORATORY
MELISA Institute's laboratory stands out for its commitment to excellence in biomedical research. With a comprehensive approach, the laboratory is composed of specialized areas in proteomics and genomics, in addition to having a robust biorepository of clinical samples, allowing for an exhaustive and multidimensional analysis of biological data. Equipped with state-of-the-art technology, MELISA Institute guarantees the highest standard of quality and precision in each of its projects, ensuring reliable and relevant results for science and medicine. Its infrastructure and interdisciplinary approach form the basis for innovative and high-impact research in the field of biotechnology.
PROTEOMICS
Through mass spectrometry techniques applied to proteomics such 35 LFQ (Label-free quantification), and TMT (Tandem M355 Tag) we can elucidate in different biological fluids the signals of communication between the human embryo and its mother. Highly specific therapeutics can be achieved by studying cell signaling through proteins and biological trophic factors. Protein identification and quantification are crucial to identify unknown compounds produced during the early stages of embryo development. We achieve this through the use of cutting-edge mass spectrometry.
timsTOF Pro 2 (Bruker)
At MELISA Institute, we have an advanced timsTOF Pro 2 mass spectrometer, designed to offer exceptional resolution and high precision in the analysis of proteins and peptides. Along with this equipment, we have the nanoElute and EVOSEP One liquid chromatographs, which provide efficient and detailed separation of compounds, optimizing data quality and reproducibility. The nanoElute stands out for its separation capacity at extremely low flow rates, while the EVOSEP One is recognized for its high efficiency and flexibility in the analysis of complex samples.
Evosep ONE
nanoElute
Äkta avant 25
At MELISA Institute, in addition to our impressive analytical equipment, we have the Akta AVANT liquid chromatograph, a cutting-edge system for the purification and analysis of biomolecules. This equipment is distinguished by its high resolution capacity and flexibility, allowing the efficient separation of proteins, peptides and other biomolecules with great precision and reproducibility. Its modular design and intuitive interface facilitate effective handling adapted to the specific needs of each investigation.
Other proteomic equipment
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IRSPirit Fourier Transform Infrared spectrophotometer
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DirectDect Spectrometer Infrared
GENOMICS
NextSeq 500
At the MELISA Institute, we work with the latest techniques in DNA / RNA sequencing (next-generation sequencing), which opens up our research capabilities in very detailed and specific regions of the human genome and transcriptome. This biomedical research approach opens a paradigm of personalized maternal-embryonic health research through precision medicine. One of the most outstanding equipment in the genomics area of ​​MELISA Institute is the Illumina NextSeq 500 next-generation sequencer. This advanced system allows high-throughput sequencing with great precision, offering an optimal balance between data capacity and speed in processing. The NextSeq 500 is ideal for a wide range of genomic applications, from gene expression studies to genetic variant analysis, thanks to its versatility and its ability to generate high-quality results in a compact and efficient format.
Other genomic equipment
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Real-time PCR Step One Plus
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Qubit 4 Fluorometer
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Fragment Analyzer Qsep 100
BIOREPOSITORY
Our clinical team collects tissue samples that are securely receipt, processed, and stored in our state of the art Biorepository, allowing our team of researchers to work with samples that will help us advance new breakthrough discoveries that will impact the wellbeing of patients.
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Sample integrity is essential for laboratory research best practices. Our cold storage unit is equipped with -80 °C freezer banks and liquid nitrogen storage tanks, currently providing our Biorepository with the capacity of preserving 1,400 liters of samples.